General Information

  • ID:  hor001449
  • Uniprot ID:  P41853
  • Protein name:  FMRFamide-like neuropeptide RYIRF-amide
  • Gene name:  NA
  • Organism:  Arthurdendyus triangulatus (New Zealand flatworm) (Artioposthia triangulata)
  • Family:  FARP (FMRFamide related peptide) family
  • Source:  Animal
  • Expression:  nervous system
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Arthurdendyus (genus), Caenoplaninae (subfamily), Geoplanidae (family), Geoplanoidea (superfamily), Continenticola (suborder), Tricladida (order), Seriata, Rhabditophora (class), Platyhelminthes (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  RYIRF
  • Length:  5(1-5)
  • Propeptide:  RYIRF
  • Signal peptide:  NA
  • Modification:  T5 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor001449_AF2.pdbhor001449_ESM.pdb

Physical Information

Mass: 82542 Formula: C36H55N11O7
Absent amino acids: ACDEGHKLMNPQSTVW Common amino acids: R
pI: 11.15 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 2
Hydrophobicity: -60 Boman Index: -2208
Half-Life / Aliphatic Index: 1 hour Aliphatic Index: 78
Instability Index: -708 Extinction Coefficient cystines: 1490
Absorbance 280nm: 372.5

Literature

  • PubMed ID:  7909164
  • Title:  RYIRFamide: A Turbellarian FMRFamide-related Peptide (FaRP)